Ketoconazole

We H&Z® have a professional, efficiency team to provide quality service for our customer. We always follow the tenet of customer-oriented, details-focused for China Factory for China Medical Grade Stable Supply High Quality Ketoconazole CAS 65277-42-1, We welcome new and old clients from all walks of lifestyle to speak to us for potential organization relationships and mutual success! China Factory for China Ketoconazole, 65277-42-1, We now have developed large markets in many countries, such as Europe and the United States, Eastern Europe and Eastern Asia. Meanwhile with the powerful predominance in persons with ability, strict production management and business concept.we constantly carry on self-innovation, technological innovation, managing innovation and business concept innovation. To follow the world markets fashion, new products are kept on researching and providing to guarantee our competitive advantage in styles, quality, price and service.

China Ketoconazole Factory

Ketoconazole CAS:65277-42-1

Ketoconazole Chemical Properties
MF:C26H28Cl2N4O4
MW:531.43
EINECS:265-667-4
Melting point:146°C
Boiling point :753.4±60.0 °c(predicted)
Density:1.4046 (rough estimate)
Refractive index:-10.5 ° (c=0.4, chcl3)
Fp :9℃
Solubilitymethanol: Soluble50mg/ml
Pka:Pka 3.25/6.22(h2o,t =25,i=0.025) (uncertain)
Optical activity:[α]20/D -1 to 1°, c = 4 in methanol
Water Solubility:Soluble in DMSO, ethanol, chloroform, water, and methanol.

Ketoconazole CAS:65277-42-1 Introduction
H&Z® Ketoconazole is a synthetic antifungal used to prevent and treat fungal skin infections, especially in immunocompromised patients such as those with AIDS or those on chemotherapy.
Ketoconazole is sold commercially as an anti-dandruff shampoo, topical cream, and oral tablet

Ketoconazole CAS:65277-42-1 Specification:

Test	Specifications	Result
Assay by HPLC	98%	99.27%
Appearance	Yellow fine powder	Complies
Odor & taste	Slight bitter	Complies
Mesh size	100% pass 80 mesh	Complies
Solubility	Soluble in water	Complies
Loss on drying	≤2.0%	1.15%
Heavy metals PPM Microbiology Total Plate Count Yeast & Mold E.Coli S.Aureus Salmonella	<30ppm   <1000cfu/g <100cfu/g Negative Negative Negative	Complies   800cfu/g 90cfu/g Complies Complies Complies

Ketoconazole CAS:65277-42-1 Function 
Ketoconazole is usually prescribed for fungal infections of the skin and mucous membranes, such as athlete's foot, ringworm, candidiasis (yeast infection or thrush), jock itch, and tinea versicolor.
Topical ketoconazole is also used as a treatment for dandruff (seborrheic dermatitis of the scalp) and for seborrheic dermatitis on other areas of the body, perhaps acting in these conditions by suppressing levels of the fungus Malassezia furfur on the skin.

Ketoconazole CAS:65277-42-1 Application 
1.Hair loss
Ketoconazole shampoo in conjunction with an oral 5α-reductase inhibitor has been used off label to treat and rogenic alopecia.
The antifungal properties of ketoconazole reduce scalp microflora and consequently may reduce follicular inflammation that contributes to alopecia.Limited clinical studies suggest ketoconazole shampoo used either alone or in com-bination with other treatments may be useful in reducing hair loss. At least one study has been performed showing that ketoconazole may be useful in temporarily reducing erectile function in postoperative penile surgery patients.
2.Veterinary use
H&Z® Ketoconazole is also sometimes prescribed by veterinarians for use on pets, often as unflavored that may need to be cut to smaller size for correct dosage.